Study Description

    Development of an improved psychometric test battery for fatigue detection
    Principal Investigator in charge: Joshua J. Gooley, Ph.D.
    Study contact:
    Location of study: Singapore General Hospital, Block 7, Level 7 (IMU)

    What is the purpose of the study?
    In this study, we are investigating the effects of alcohol and sleep deprivation on cognition and driving simulator performance. This research could help us to identify novel markers of fatigue. Who can take part in the study? Healthy males who are 21-40 years old can take part in the study. You must hold a motorcar driver’s license. You must be a casual drinker, which means that you consume on average between 1-6 alcoholic beverages during a typical week. If you have an alcohol flush reaction (your face turns red when you drink alcohol) you cannot take part in this study. You cannot take any drugs or medications while you are enrolled in the study. You must be willing to avoid consumption of caffeine, alcohol, nicotine products, and over-the-counter medications for one week prior to the laboratory study. To find out if you are eligible, we will ask you to fill out forms which take about 1-2 hours to complete. If you are eligible and willing to participate, you will come back to the research laboratory for the main study.

    How long is the study?
    The study includes two laboratory visits spaced apart by at least 2 weeks. During each visit, you will stay in our sleep laboratory at the Singapore General Hospital (SGH) for 3 days at a time. Therefore, you will stay in the lab for a total of 6 days (summed across both visits).

    What happens during the study?
    You will stay in a research suite that is similar to a small studio apartment. It has a bedroom/study area and a bathroom with shower. There is a media player that you can use for watching recorded movies/television/music. There are no clocks, windows, radios, or anything else that would tell you the time of day. You cannot have visitors and you cannot make or receive phone calls. During each laboratory visit, you will stay awake overnight (for about 25 consecutive hours). During one of the study visits, you will drink small doses of alcohol over several hours. After the final dose of alcohol, your blood alcohol level will be about 100 mg/dL, which is above the legal limit for driving a vehicle in Singapore. You will take computer tests and a simulating driving task every 1 to 2 hours. We will take frequent breathalyzer measurements during the procedure, and you will be monitored until your body is clear of alcohol. You will not have much free time during the laboratory study.

    Do I get reimbursed?
    Yes, you will receive $1000 if you complete all study requirements (both 3-day lab visits). If you decide to quit the study early, there is no penalty and we reimburse you for what you completed.

    Questions: Please direct any questions about the study to

    Posted on: 5/2/2017
Please email to for more information if you are interested in participating.
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